CHEMICAL CHANGES IN THE BLOOD OF THE DOG AFTER PYLORIC OBSTRUCTION

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Chemical Changes in the Blood of the Dog after Pyloric Obstruction

Chemical studies of the blood and urine of four dogs following pyloric obstruction are reported. The observations of other workers that a fall in chlorides and a rise in CO(2)-combining power of the plasma occur, are confirmed. There is also a marked rise in the non-protein nitrogen of the blood, consisting mainly of urea nitrogen and undetermined nitrogen. The fall in chlorides is not due to t...

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The Effect of Sodium Chloride on the Chemical Changes in the Blood of the Dog after Pyloric and Intestinal Obstruction

Experiments to determine the effect of furnishing an ample supply of sodium chloride on the toxemia of pyloric and intestinal obstruction are reported. A fall in chlorides is the first and seemingly most significant change to take place in the blood after pyloric and intestinal obstruction. The chloride is apparently utilized by the body as a protective measure against the primary toxic substan...

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The Effect of Inorganic Salts on the Chemical Changes in the Blood of the Dog after Obstruction of the Duodenum

The chemical changes in the blood of dogs treated with various inorganic salts after obstruction of the duodenum are reported. Two dogs treated with sodium chloride survived approximately six times as long as the average untreated animal, one living 22 days, the other 24 days. Ammonium chloride was found to produce an acidosis. The administration of potassium chloride, calcium chloride, and mag...

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Chemical Findings in the Blood of the Dog after Temporary Obstruction of the Pylorus

The toxemia characteristic of upper gastrointestinal tract obstruction may be produced by temporary obstruction of the pylorus. This procedure affords an opportunity for studying the toxemia in the absence of mechanical factors, operative risk, and infection. Animals which spontaneously recover from the toxemia may show a return of the blood chloride to normal when only distilled water is given...

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ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1923

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.37.3.377